cicCartuja Centro de Investigaciones Científicas de la cartuja

  • Jobs & Training>>
  • Bacterial behavior on coated porous titanium substrates for biomedical applications
< Javier Castillo premio al mejor TFM en ciencia de materiales 2019
10 December 2019 12:03 Age: 1 Years

Bacterial behavior on coated porous titanium substrates for biomedical applications


Dra.  Ana M. Beltrán Custodio

Martes, 10 de diciembre de 2019. 10:00 h

Seminario de cicCartuja2

Abstract

In this work, bacterial behavior on dense and porous titanium substrates is discussed. Porous titanium was fabricated by a space holder technique (using 50 vol%, NH4HCO3 with particle sizes between 250 and 355 μm). These substrates were coated by sulfonated PEEK (termed SPEEK). Characterization of the porous substrate was carried out using the Archimedes Method, Image Analysis, and three-dimensional X-ray Micro-Computed Tomography (including total and interconnected porosity, equivalent diameter, and pore shape factor), as well as mechanical characterization (specifically stiffness and yield strength).

A detailed study was performed here to investigate the influence of substrate porosity on the adhesion and proliferation of E. coli, MRSA, and P. aeruginosa (common causes of orthopedic device-associated infections). Bacterial colonization was examined in terms of the initial bacterial concentration, as well as bacterial adherence to and growth on the surface and inside the pores. Results suggest that fully dense titanium supported the least bacterial colonization, while the porous titanium promoted bacterial growth in the medium and inside the cavities.

Furthermore, the SPEEK coating deposited onto the samples inhibited bacteria growth inside the porous materials. In this manner, this study showed for the first time that SPEEK could have potential antibacterial properties to offset the increase in bacteria growth commonly observed in porous materials. 


Center News

4 June 2018

I Jornada de Prevención de Acoso Sexual y Laboral

Dirigido a todo el personal de los centros CSIC y de otros organismos de investigación. INSCRIPCIONES hasta el 8 JUNIO


1 June 2018

Jornada de formación: Digital CSIC y acceso abierto

El viernes 8 de junio se celebra en cicCartuja una jornada de formación para explicar los servicios a la comunidad de Digital CSIC


24 May 2018

El IBVF en la Jornadas de la Ciencia del IES Munigua

El IBVF participa con un stand en este evento de divulgación científica celebrado en Villanueva del Río y Minas.


16 May 2018

Ernesto Carmona (IIQ), medalla a toda una vida de investigación

Medalla de oro del Colegio de Químicos del Sur por sus contribuciones en el campo de la química de los compuestos organometálicos.


16 May 2018

El cicCartuja acoge a la Red sobre Sistemas de Transporte Iónico en Plantas

Del 16 al 17 de mayo se celebra la 5ª reunión de esta red de Excelencia financiada por la Agencia Estatal de Investigación.


11 May 2018

Zeolites and Metal-Organic Frameworks: From Lab to Industry

Luis F. Bobadilla (ICMS) es uno de los tres editores de este monográfico publicado por la Amsterdam University Press.


10 May 2018

Jose L. Pérez-Rodríguez (ICMS), recibe el David Dollimore ESTAC Award

La Asociación Europea de Análisis Térmico otorga este galardón a profesores o investigadores eméritos.