Structure and support induced structure disruption of soft nanoparticles obtained from hydroxylated fatty acids
Soft and spherical nanoparticles, named as cutinsomes, have been prepared from concentrated 9(10),16-dihydroxypalmitic acid (diHPA) in aqueous solution. After isolation, cutinsomes have been chemically and structurally characterized by ATR-FTIR, TEM and dynamic atomic...
Copper-Catalyzed Azide–Alkyne Cycloaddition in the Synthesis of Polydiacetylene: «Click Glycoliposome» as Biosensors for the Specific Detection of Lectins
Supramolecular self-assembly of conjugated diacetylenic amphiphile-tethered ligands photopolymerize to afford polydiacetylene (PDA) functional liposomes. Upon specific interaction with a variety of biological analytes in aqueous solution, PDA exhibits rapid...
Inhibition of Arabidopsis O-Acetylserine(thiol)lyase A1 by Tyrosine-Nitration
The last step of sulfur assimilation is catalyzed by O‐acetylserine(thiol)lyase (OASTL) enzymes. OASTLs are encoded by a multigene family in the model plant Arabidopsis thaliana. Cytosolic OASA1 enzyme is the main source of OASTL activity and thus crucial for cysteine...
Gold supported on metal-doped ceria catalysts (M=Zr, Zn and Fe) for the preferential oxidation of CO (PROX)
A series of ceria oxides doped with 10 mol.% of Zr, Zn and Fe has been prepared by a pseudo sol‐gel method throughout the thermal decomposition of the corresponding metallic propionates. With these supports, 1 wt.% gold catalysts were prepared by the deposition-...
Polycationic Amphiphilic Cyclodextrins for Gene Delivery: Synthesis and Effect of Structural Modifications on Plasmid DNA Complex Stability, Cytotoxicity, and Gene Expression
A molecular-diversity-oriented approach for the preparation of well-defined polycationic amphiphilic cyclodextrins paCDs) as gene-delivery systems is reported. The synthetic strategy takes advantage of the differential reactivity of primary versus secondary hydroxyl...