The yeast autophagy protease Atg4 is regulated by thioredoxin
En portadaThe yeast autophagy protease Atg4 is regulated by thioredoxin Desde los sistemas más simples, como las levaduras o las microalgas unicelulares, hasta los más complejos, como las plantas o los animales, todos los organismos eucariotas activan diferentes...
Cytochrome c1 exhibits two binding sites for cytochrome c in plants
In plants, channeling of cytochrome c molecules between complexes III and IV has been purported to shuttle electrons within the supercomplexes instead of carrying electrons by random diffusion across the intermembrane bulk phase. However, the mode plant cytochrome c...
Oxidative stress contributes to autophagy induction in response to endoplasmic reticulum stress in Chlamydomonas
The accumulation of unfolded/misfolded proteins in the endoplasmic reticulum (ER) results in the activation of stress responses such as the unfolded protein response or the catabolic process of autophagy to ultimately recover cellular homeostasis. ER stress also...
The binding of TIA-1 to RNA C-rich sequences is driven by its C-terminal RRM domain
T-cell intracellular antigen-1 (TIA-1) is a key DNA/RNA binding protein that regulates translation by sequestering target mRNAs in stress granules (SG) in response to stress conditions. TIA-1 possesses three RNA recognition motifs (RRM) along with a glutamine-rich...