Water-Promoted Generation of a Diazairida Homobarrelene by C—C Coupling Between an Iridacyclic Alkylidene and Acetonitrile
The stable cationic iridacyclopentenylidene [TpMe2Ir(=CHC(Me)=C(Me)CH2(NCMe)]PF6(A;TpMe2=hydrotris (3,5dimethylpyrazolyl)borate) has been obtained by α-hydride abstraction from the iridacyclopent-2-ene [TpMe2Ir(CH2C(Me)=C(Me)CH2)(NCMe)]. Complex A exhibits...![A Diels–Alder Reaction Triggered by a [4 + 3] Metallacycloaddition](https://www.ciccartuja.es/wp-content/uploads/sites/4/2024/11/15_06.jpg)
A Diels–Alder Reaction Triggered by a [4 + 3] Metallacycloaddition
The TpMe2Ir(III) complex 1-OH2 (TpMe2 = hydrotris(3,5-dimethylpyrazolyl)borate), which contains a labile molecule of water and an iridium-bonded alkenyl moiety (−C(R)═C(R)–(R=CO2Me)) as part of a benzo-annulated five-membered iridacycle, reacts readily with the...
Langerin–Heparin Interaction: Two Binding Sites for Small and Large Ligands As Revealed by a Combination of NMR Spectroscopy and Cross-Linking Mapping Experiments
Langerin is a C-type lectin present on Langerhans cells that mediates capture of pathogens in a carbohydrate-dependent manner, leading to subsequent internalization and elimination in the cellular organelles called Birbeck granules. This mechanism mediated by langerin...
Asymmetric Hydrogenation of 1-Alkyl and 1-Aryl Vinyl Benzoates: A Broad Scope Procedure for the Highly Enantioselective Synthesis of 1-Substituted Ethyl Benzoates
En portadaAsymmetric Hydrogenation of 1-Alkyl and 1-Aryl Vinyl Benzoates: A Broad Scope Procedure for the Highly Enantioselective Synthesis of 1-Substituted Ethyl Benzoates Investigadores del Instituto de Investigaciones Químicas del cicCartuja y de la Universidad de...