Multisite phosphorylation of the AML-linked C-terminal of nucleophosmin (NPM1) orchestrates protein stability, DNA binding and charge block-driven phase separation
Nucleophosmin (NPM1) is a nucleolar protein commonly mutated in ~30% of newly diagnosed acute myeloid leukemia (AML) cases. These mutations occur in the terminal exon of the NPM1 gene, affecting the C-terminal DNA-binding domain of the protein and causing its...
A study improves advanced medical ceramics to slow the deterioration of orthopaedic prostheses
The incorporation of two-dimensional boron nitride, known as ‘white graphene’, into zirconia ceramics increases the strength of this material—used in hip, dental and knee prostheses—by 18% A study led by the Institute of Materials Science of Seville (ICMS), a joint...
CSIC researchers identify photocatalysis as a key technology for driving solutions in health, energy and the environment
Marta Castellote (IETCC), Gerardo Colón (ICMS) and José Luis Hueso (INMA) have coordinated a report as part of the ‘Science4Policy’ programme, in which they analyse the potential applications and future challengesThe ‘Conexión Fotocatálisis’ scientific network, which...
IBVF organizes the workshop on public–private opportunities in the agricultural sector at cicCartuja
Workshop: Public–private opportunities in the agricultural sector CicCartuja, April 15, 2026 9:30–9:45: Presentation of the workshop 9:45–10:15 José Antonio Pascual Sánchez. Head of the R&D Department of the Andalucía TRADE Agency. Business Financing Directorate....