Characterization of the kisspeptin system in human spermatozoa

Characterization of the kisspeptin system in human spermatozoa

Kisspeptin, the product of the KISS1 gene, plays an essential role in the regulation of spermatogenesis acting primarily at the hypothalamic level of the gonadotropic axis. However, the presence of kisspeptin and its canonical receptor, KISS1R, in spermatozoa has not...
“On Water” Nucleophilic Addition of Formaldehyde N,N-Dialkylhydrazones to α-Keto Esters

“On Water” Nucleophilic Addition of Formaldehyde N,N-Dialkylhydrazones to α-Keto Esters

Water solves the problem: The use of pure water as the reaction mixture is key for the nucleophilic addition of formaldehyde hydrazones to α-keto esters, leading to highly functionalized carbinols in high yields and short reaction times. The need for heterogeneous...
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