Broad Scope Synthesis of Ester Precursors of Nonfunctionalized Chiral Alcohols Based on the Asymmetric Hydrogenation of α,β- Dialkyl-, α,β- Diaryl-, and α-Alkyl-β-aryl-vinyl Esters

Broad Scope Synthesis of Ester Precursors of Nonfunctionalized Chiral Alcohols Based on the Asymmetric Hydrogenation of α,β- Dialkyl-, α,β- Diaryl-, and α-Alkyl-β-aryl-vinyl Esters

Dec 26, 2017 | Papers of the Month, Papers of the Month, Papers of the Month, Papers of the Month, Papers of the Month

The catalytic asymmetric hydrogenation of trisubstituted enol esters using Rh catalysts bearing chiral phosphinephosphite ligands (P-OP) has been studied. Substrates covered comprise α,β-dialkyl, α-alkyl-β-aryl, and α,β-diarylvinyl esters, the corresponding...
WordPress Appliance - Powered by TurnKey Linux