Dec 27, 2010 | Uncategorized
A molecular-diversity-oriented approach for the preparation of well-defined polycationic amphiphilic cyclodextrins paCDs) as gene-delivery systems is reported. The synthetic strategy takes advantage of the differential reactivity of primary versus secondary hydroxyl...
Nov 27, 2010 | Papers of the Month, Papers of the Month, Papers of the Month, Papers of the Month, Papers of the Month, Papers of the Month
We have developed an efficient strategy for the non-covalent functionalization of multi-wall carbon nanotubes (MWCNTs) which allows a biomimetic presentation of carbohydrates on their surface by π-π stacking interactions. The strategy is based on the use of...
Oct 27, 2010 | Uncategorized
The use of both supported and flexible self-standing nanoparticle-based one dimensional photonic crystal films as effective frequency selective filters in the UV-vis-NIR is herein evaluated. The requirements to achieve a flat spectral response at the desired frequency...
Sep 27, 2010 | 2010, 2010, 2010, 2010, 2010, 2010
Tyrosine nitration is one of the most common post-transcriptional modifications of proteins, so affecting their structure and function. Human cytochrome c, with five tyrosine residues, is an excellent case study as it is a well-known protein playing a double...
Aug 27, 2010 | Uncategorized
A new catalyst type for a new reaction. The unprecedented cyanosilylation of nitroalkenes can be efficiently catalyzed by a bifunctional quinine derivative bearing tetra-alkylammonium cyanide and thiourea moieties. The activation of the nitroalkene by H-bonding to the...
Jul 27, 2010 | Uncategorized
Autophagy is a catabolic membrane-trafficking process whereby cells recycle cytosolic proteins and organelles under stress conditions or during development. This degradative process is mediated by autophagy-related (ATG) proteins which have been described in yeasts,...