Reductive C–C Coupling from Molecular Au(I) Hydrocarbyl Complexes: A Mechanistic Study
Organometallic gold complexes are used in a range of catalytic reactions, and they often serve as catalyst precursors that mediate C–C bond formation. In this study, we investigate C–C coupling to form ethane from various phosphine-ligated gem-digold(I) methyl...
Tuning the Topological Landscape of DNA-Cyclodextrin Nanocomplexes by Molecular Design
Original molecular vectors that ensure broad flexibility to tune the shape and surface properties of plasmid DNA (pDNA) condensates are reported herein. The prototypic design involves a cyclodextrin (CD) platform bearing a polycationic cluster at the primary face and...
Reversible Hydride Migration from C5Me5 to RhI Revealed by a Cooperative Bimetallic Approach
The use of cyclopentadienyl ligands in organometallic chemistry and catalysis is ubiquitous, mostly due to their robust spectator role. Nonetheless, increasing examples of non‐innocent behaviour are being documented. Here, we provide evidence for reversible...
Exploring protein phosphorylation by combining computational approaches and biochemical methods
Post-translational modifications of proteins expand their functional diversity, regulating the response of cells to a variety of stimuli. Among these modifications, phosphorylation is the most ubiquitous and plays a prominent role in cell signaling. The addition of a...