Base-Promoted, Remote C−H Activation at a Cationic (η5‐C5Me5)Ir(III) Center Involving Reversible C−C Bond Formation of Bound C5Me5
C−H bond activation at cationic [(η5-C5Me5)Ir(PMe2Ar′)] centers is described, where PMe2Ar′are the terphenyl phosphine ligands PMe2ArXyl2 and PMe2ArDipp 2. Different pathways are defined for the conversion of the five-coordinate complexes [(η5-C5Me5)-IrCl(PMe2Ar′)]+,...
Dynamic Kinetic Asymmetric Heck Reaction for the Simultaneous Generation of Central and Axial Chirality
A highly diastereo- and enantioselective, scalable Pd-catalyzed dynamic kinetic asymmetric Heck reaction of heterobiaryl sulfonates with electron-rich olefins is described. The coupling of 2,3-dihydrofuran or N-boc protected 2,3-dihydropyrrole with a variety of...
Oxidative stress is tightly regulated by cytochrome c phosphorylation and respirasome factors in mitochondria
Respiratory cytochrome c has been found to be phosphorylated at tyrosine 97 in the postischemic brain upon neuroprotective insulin treatment, but how such posttranslational modification affects mitochondrial metabolism is unclear. Here, we report the structural...
Isolation of a Cationic Platinum(II) s-Silane Complex
The platinum complex [Pt(ItBuiPr′)(ItBuiPr)][BArF] interacts with tertiary silanes to form stable (<0 °C) mononuclear PtII σ‐SiH complexes [Pt(ItBuiPr′)(ItBuiPr)(η1‐HSiR3)][BArF]. These compounds have been fully characterized, including X‐ray diffraction methods,...