Stepwise alkyne insertion in Au(i) acetylides: influence of the nuclearity
The reaction between NHC-supported (NHC = N-heterocyclic carbene) gold(I) trimethylsilylacetylide complexes with NHC gold(I) hydroxide species renders different symmetrical homobimetallic Au complexes. These compounds readily undergo migratory insertion of DMAD...
Jesús Campos Manzano of the IIQ and Rocío López Igual of the IBVF receive awards at the XIII Losada Villasante Awards
The prize for Scientific Research went to Jesús Campos Manzano, CSIC research scientist at the Institute of Chemical Research in Seville. The winning project is entitled ‘Design of Radical Cooperative Catalysts’. The aim is to design new strategies in catalysis, which...
STD NMR Epitope Perturbation by Mutation Unveils the Mechanism of YM155 as an Arginine-Glycosyltransferases Inhibitor Effective in Treating Enteropathogenic Diseases
Enteropathogenic arginine-glycosyltransferases (Arg-GTs) alter higher eukaryotic proteins by attaching a GlcNAc residue to arginine acceptor sites, disrupting essential pathways such as NF-κB signaling, which promotes bacterial survival. These enzymes are potential...
An open-shell Ir(II)/Ir(IV) redox couple outperforms an Ir(I)/Ir(III) pair in olefin isomerization
Open-shell systems based on first-row transition metals and their involvement in various catalytic processes are well explored. By comparison, mononuclear open-shell complexes of precious transition metals remain underdeveloped. This is particularly true for IrII...