![[60]Fullerene as Multivalent Scaffold: Efficient Molecular Recognition of Globular Glycofullerenes by Concanavalin A](https://www.ciccartuja.es/wp-content/uploads/sites/4/2024/11/ChemEurJ2011.gif)
Symmetry Complementarity‐Guided Design of Anthrax Toxin Inhibitors Based on β‐Cyclodextrin: Synthesis and Relative Activities of Face‐Selective Functionalized Polycationic Clusters
En este trabajo se describe el desarrollo de tres nuevas series de inhibidores potenciales de la toxina del Ántrax basados en la plataforma de la β‐ciclodextrina (βCD). El diseño se basa en el concepto de la ‘complementariedad de simetría’ entre derivados...
Copper-Catalyzed Azide–Alkyne Cycloaddition in the Synthesis of Polydiacetylene: “Click Glycoliposome” as Biosensors for the Specific Detection of Lectins
Supramolecular self-assembly of conjugated diacetylenic amphiphile-tethered ligands photopolymerize to afford polydiacetylene (PDA) functional liposomes. Upon specific interaction with a variety of biological analytes in aqueous solution, PDA exhibits rapid...
Polycationic Amphiphilic Cyclodextrins for Gene Delivery: Synthesis and Effect of Structural Modifications on Plasmid DNA Complex Stability, Cytotoxicity, and Gene Expression
A molecular-diversity-oriented approach for the preparation of well-defined polycationic amphiphilic cyclodextrins paCDs) as gene-delivery systems is reported. The synthetic strategy takes advantage of the differential reactivity of primary versus secondary hydroxyl...
Improved non-covalent biofunctionalization of Multi-Walled Carbon Nanotubes using Carbohydrates Amphiphiles with a Butterfly-Like Polyaromatic tail
We have developed an efficient strategy for the non-covalent functionalization of multi-wall carbon nanotubes (MWCNTs) which allows a biomimetic presentation of carbohydrates on their surface by π-π stacking interactions. The strategy is based on the use of...