Glyconanosomes: Disk-Shaped Nanomaterials for the Water Solubilization and Delivery of Hydrophobic Molecules
Herein, we describe the first report on a new class of disk-shaped and quite monodisperse water-soluble nanomaterials that we named glyconanosomes (GNS). GNSs were obtained by sliding out the cylindrical structures formed upon self-organization and photopolymerization...
Interconversion of Quadruply and Quintuply Bonded Molybdenum Complexes by Reductive Elimination and Oxidative Addition of Dihydrogen
A series of dimolybdenum dihydride complexes supported by amidinate ligands and featuring a Mo—Mo quadruple bond, MoII2, has been prepared and characterized by NMR spectroscopy and x-ray crystallography. UV irradiation (365 nm) of one of these complexes, namely the...
Virus-like glycodendrinanoparticles displaying quasi-equivalent nested polyvalency upon glycoprotein platforms potently block viral infection
Ligand polyvalency is a powerful modulator of protein–receptor interactions. In particular, host–pathogen infection interactions are often mediated by glycan ligand–protein interactions. The study of these interactions using synthetic compounds with very high copy...
Characterization of a Paramagnetic, Mononuclear Pt (II)-Alkyl Complex Intermediate in Carbon-Halogen Bond Coupling Reaction
Addition of Br2 or I2 to 14-electron, cationic Pt(II)-alkyl complexes led to the formation of the corresponding carbon-halogen Pt(II) coupling products. Low temperature experiments with Br2 allowed us to isolate and characterize crystallographically a very unusual...